While stuck at a wedding in Palm Springs, Nyles (Andy Samberg) meets Sarah (Cristin Milioti), the maid of honor and family black sheep. After he rescues her from a disastrous toast, Sarah becomes drawn to Nyles and his offbeat nihilism. But when their impromptu tryst is thwarted by a surreal interruption, Sarah must join Nyles in embracing the idea that nothing really matters, and they begin wreaking spirited havoc on the wedding celebration.

Comedy
Max Barbakow
Camila Mendes
Tyler Hoechlin
Andy Samberg
Cristin Milioti
J.K. Simmons
Jacqueline Obradors
Peter Gallagher
Dale Dickey
Meredith Hagner
June Squibb
Chris Pang
Lilli Birdsell
Conner O'Malley
Mark Kubr
Erin Flannery
Culmination Productions
Neon